Effects of kiwi consumption on plasma lipids, fibrinogen and insulin resistance in the context of a normal diet

Nutr J. 2015 Sep 15:14:97. doi: 10.1186/s12937-015-0086-0.

Abstract

Background and aims: Among fruits, kiwi is one of the richest in vitamins and polyphenols and has strong anti-oxidant effects. We aimed to analyze the relationship between the consumption of kiwi and plasma lipid values, fibrinogen, and insulin resistance in adults within the context of a normal diet and physical-activity.

Methods: Cross-sectional study. Participants (N = 1469), who were free of cardiovascular diseases, completed a visit, which included the collection of information concerning the participant's usual diet and kiwi consumption using a previously validated, semi-quantitative, 137-item food-frequency-questionnaire. Fasting laboratory determinations included plasma lipids, fibrinogen and insulin resistance. Regular physical-activity was determined using accelerometry.

Results: Consumers of at least 1 kiwi/week presented higher plasma values of HDL-cholesterol (mean difference 4.50 [95% CI: 2.63 to 6.36]) and lower triglyceride values (mean difference -20.03 [95% CI: -6.77 to -33.29]), fibrinogen values (mean difference -13.22 [95% CI: -2.18 to -24.26]) and HOMAir values (mean difference -0.30 [95% CI: -0.09 to -0.50]) (p < 0.05, for all comparisons) than those who consumed less than 1 kiwi per week. In an adjusted logistic regression analysis, this group had a lower odds-ratio for presenting plasmatic fibrinogen concentrations above 400 mg/dL (OR = 0.68, 95% CI 0.49 to 0.95), HDL-Cholesterol plasma values below 45 mg/dL (OR = 0.57, 95% CI 0.36 to 0.91) and a HOMAir above 3 (OR = 0.61, 95% CI 0.37 to 1.00).

Conclusions: Consumption of at least one kiwi/week is associated with lower plasma concentrations of fibrinogen and improved plasma lipid profile in the context of a normal diet and regular exercise.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actinidia*
  • Adult
  • Aged
  • Antioxidants / pharmacology
  • Body Mass Index
  • Cholesterol, HDL / blood
  • Cholesterol, LDL / blood
  • Cross-Sectional Studies
  • Diet*
  • Female
  • Fibrinogen / metabolism*
  • Fruit*
  • Humans
  • Insulin Resistance*
  • Life Style
  • Logistic Models
  • Male
  • Middle Aged
  • Motor Activity
  • Nutrition Assessment
  • Polyphenols / pharmacology
  • Surveys and Questionnaires
  • Triglycerides / blood

Substances

  • Antioxidants
  • Cholesterol, HDL
  • Cholesterol, LDL
  • Polyphenols
  • Triglycerides
  • Fibrinogen